Back to results
US 8,044,051 B2Granted
Methods and compositions for the production of high concentration alloxazine solutions
AssigneeCaridianBCT Biotechnologies, LLC
InventorsEric T. Hansen, Raymond P. Goodrich
Life of this patent
Estimating the term…
Abstract
Methods are provided for preparation of compositions having an enhanced level of soluble alloxazine, as compared to compositions prepared using conventional techniques. Compositions and a riboflavin form having higher solubility in solution is also provided.
Claims3
A method of increasing the concentration of an alloxazine in an aqueous medium consisting of sodium chloride to above the alloxazine's saturation point, the method comprising:
- adding an amount of said alloxazine to an aqueous medium consisting of about 0.9% sodium chloride at a pH of between about 4 and about 5, wherein the amount of alloxazine exceeds the saturation point of said alloxazine at 1 atmosphere and 22° C:
- heating said aqueous medium consisting of sodium chloride and alloxazine to a temperature between about 80° C. and about 90° C;
- and
- cooling said aqueous medium consisting of sodium chloride and alloxazine to produce an aqueous medium having a concentration of alloxazine above the alloxazine saturation point.
1 more element
Dependencies are inferred from the claim text.