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US 8,043,270 B2Granted
Pharmaceutical analysis apparatus and method
AssigneeGlaxoSmith Kline LLC
InventorsMatthew D Burke, Chinmay R Maheshwari, Brian O Zimmerman
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Abstract
An apparatus and method are provided for analyzing the release of active agent(s) from pharmaceutical and pharmaceutical-like products. The apparatus and method provide for more accurate simulation of the conditions in the GI tract including forces that are applied to the dosage form.
Claims12
A dissolution device to analyze the release of an active agent from a dosage form in a GI tract, the device comprising:
- a vessel having an open end, said vessel containing a medium;
- and
- a force application system having a chamber and a force imparting mechanism,
- said chamber supporting the dosage form and being in fluid communication with said medium, wherein said force imparting mechanism applies compression to the dosage form to simulate conditions in the GI tract.
1 more element
Dependencies are inferred from the claim text.