Fluorescent protein
AssigneeRiken
InventorsAtsushi Miyawaki, Ryoko Ando, Hideaki Mizuno, Satoshi Karasawa
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Abstract
The object of the present invention is to provide a novel fluorescent protein in which on and off of fluorescence thereof can be controlled by irradiation with lights of two different wavelengths. The present invention provides a fluorescent protein shown in the following (a) or (b); (a) a protein which has the amino acid sequence shown in SEQ ID NO: 3 or 7; or (b) a protein which has an amino acid sequence comprising a deletion, substitution, and/or addition of one or several amino acids with respect to the amino acid sequence shown in SEQ ID NO: 3 or 7, and which has fluorescence characteristics of exhibiting a photochromic effect.
Claims6
A fluorescent protein shown in the following (a) or (b);
- (a) a protein which has the amino acid sequence shown in SEQ ID NO:
- 3;
- or
- (b) a protein which has an amino acid sequence comprising a deletion, substitution, and/or addition of one to twenty amino acids of SEQ ID NO:
- 3, and has a methionine residue at a corresponding to position 159, and a glutamic acid residue at a position corresponding to position 218 of SEQ ID NO:
- 3, and which has fluorescence characteristics of exhibiting a photochromic effect.
Dependencies are inferred from the claim text.