Drug delivery catheters that attach to tissue and methods for their use
AssigneeBioCardia, Inc.
InventorsPeter A. Altman, John D. Altman, Simon Stertzer
Life of this patent
Estimating the term…
Abstract
A drug delivery catheter suited for cardiac procedures. The catheter includes a distal helical coil or other fixation and penetrating element which can be operated from the proximal end of the catheter to engage and penetrate the myocardium. Once delivered to the inside of the heart, the catheter can be used to inject small doses of therapeutic agents to the myocardium. The drug delivery system of the catheter allows for precise control of the dose injected into the heart wall.
Claims17
A method of delivery of a therapeutic agent to a depth within the myocardium including the steps of:
- inserting a catheter into the heart, said catheter having a proximal end and a distal end, said catheter configured with a fixating penetrating element secured to the distal end thereof, said catheter having a therapeutic agent lumen extending from the proximal end to the distal end of the catheter, a therapeutic agent port at the distal end of the catheter communicating from the therapeutic agent lumen to the exterior of the catheter and a contrast delivery lumen extending from the proximal end to the distal end of the catheter and a contrast port communicating from the contrast agent lumen to the exterior of the catheter proximal to the fixating penetrating element;
- accessing the heart with the catheter percutaneously through a blood vessel of the patient and into an endocardial space in the heart, and
- manipulating the fixating penetrating element to engage and penetrate the heart wall and releasably connect the catheter distal tip to the heart wall;
- and
- infusing a therapeutic agent to a depth within the heart wall.
A catheter adapted for insertion into the heart, said catheter comprising:
- a catheter body having a proximal end and a distal end and configured for percutaneous insertion into an endocardial space within the heart through a blood vessel;
- a resilient coil having a proximal end and a distal end, said proximal end of the resilient coil secured to the distal end of the catheter body;
- a fixating penetrating element secured to the distal end of the resilient coil;
- a drug delivery lumen extending from the proximal end to the distal end of the catheter and a drug delivery port at the distal end of the catheter communicating from the drug delivery lumen to the exterior of the catheter through the penetrating element;
- and
- a contrast delivery lumen extending from the proximal end to the distal end of the catheter communicating from the contrast agent lumen to the exterior of the catheter proximal to the penetrating element.
Dependencies are inferred from the claim text.