Method for obtaining an aminoindan mesylate derivative
AssigneeMedichem, S.A.
InventorsJordi Boschi I Llado, Maria Carmen Burgarolas Montero, Judit Masllorens Llinas
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Abstract
The invention relates to processes for preparing rasagiline mesylate that avoid the use of alcohol solvents, thereby producing rasagiline mesylate free of any alkyl mesylates, including isopropyl mesylate. The invention further relates to processes for purifying rasagiline mesylate to obtain a product free of alkyl mesylates, and to the thus obtained rasagiline mesylate.
Claims18
Rasagiline mesylate free of hydroxylic solvents.
Rasagiline mesylate free of alkyl mesylates.
Rasagiline mesylate free of alkyl mesylates made by the process comprising:
- treating at least one of rasagiline free base and an acid addition salt thereof with methanesulfonic acid and in the presence of a non-hydroxylic solvent.
Rasagiline mesylate free of alkyl mesylates made by the process comprising:
- contacting rasagiline mesylate with a non-hydroxylic solvent.
A composition comprising:
- rasagiline mesylate,
- wherein the composition is free of hydroxylic solvents.
A composition comprising:
- rasagiline mesylate,
- wherein the composition is free of alkyl mesylates.
An active pharmaceutical ingredient consisting of rasagiline mesylate free of alkyl mesylates and hydroxylic solvents.
Dependencies are inferred from the claim text.