Characterization and identification of unique human adiponectin isoforms and antibodies
AssigneeHoffmann-La Roche Inc.
InventorsCharles Roger Burghardt, Jarema Peter Kochan, Erik Roy Rasmussen
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Abstract
The invention pertains to methods for measuring different forms of human adiponectin that are present in human plasma/serum, and more specifically methods are based on an ELISA assay that utilizes different monoclonal antibodies directed against adiponectin, in combination with different polyclonal antibodies directed against different domains of human adiponectin. The invention also provides unique isoforms of adiponectin and antibodies thereto, including polyclonal and monoclonal antibodies.
Claims2
A purified adiponectin antibody comprising SEQ ID NO:18.
A purified adiponectin antibody comprising SEQ ID NO:19.
Dependencies are inferred from the claim text.