Light filters comprising a naturally occurring chromophore and derivatives thereof
AssigneeBenz Research and Development Corporation
InventorsPatrick H. Benz, Jose A. Ors
Life of this patent
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Abstract
A composition comprising a polymer backbone and at least one side group, wherein the side group comprises a benzene ring-based chromophore comprising a ketone at the 1-position, a substituted or unsubstituted amino group at the 2-position, and an oxygen atom at the 3-position of the benzene ring. The chromophore is a kynurenine-based compound. Methods of making and using the composition are also provided. The composition can be used in an ophthalmic lens or device for protecting the retina by blocking UV rays and filtering violet rays.
Claims36
A composition comprising:
- a polymer comprising a polymer backbone and at least one side group, wherein the side group comprises a benzene ring-based chromophore comprising a ketone at the 1-position, a substituted or unsubstituted amino group at the 2-position, and an oxygen atom at the 3-position of the benzene ring, and
- wherein the chromophore does not comprise an oxidative polymerization product of 3-hydroxykynurenine.
A method of making comprising:
- providing a at least one polymerization monomer,
- optionally providing at least one additional polymerization monomer, and
- polymerizing the at least one polymerization monomer, and
- wherein the at least one polymerization monomer comprises a polymerizable vinyl group covalently linked to a benzene ring-based chromophore comprising a ketone at the 1-position, a substituted or unsubstituted amino group at the 2-position, and an oxygen atom at the 3-position of the benzene ring, wherein the chromophore does not comprise an oxidative polymerization product of 3-hydroxykynurenine.
A method of making an ophthalmic lens or device comprising:
- providing a compound according to formula (I):
- wherein R1 is H, an alkyl group, or comprises an amino acid moiety or derivative thereof;
- wherein R2 and R3 are individually H, alkyl, or any moiety with a vinyl functionality;
- wherein R4 is an alkyl group, any moiety with a vinyl functionality, a counterpart alkylene group, or a sugar moiety;
- and wherein X is an optional electron-donating group linked to the benzene ring at the 4, 5, or 6 position;
- optionally providing at least one additional polymerization monomer;
- and
- polymerizing the polymerization monomer and optional compound.
A method of using a compound comprising:
- providing a compound according to formula (I):
- wherein R1 is H, an alkyl group, or comprises an amino acid moiety or derivative thereof
- wherein R2 and R3 are individually H, alkyl, or any moiety with a vinyl functionality;
- wherein R4 is an alkyl group, any moiety with a vinyl functionality, a counterpart alkylene group, or a sugar moiety;
- and
- wherein X is an optional electron-donating group linked to the benzene ring at the 4, 5, or 6 position;
- polymerizing the compound;
- and
- polymerizing the compound and optionally the additional polymerization monomer;
- and placing the polymerized compound in an opthalmic lens or device.
An device comprising:
- a polymer comprising a polymer backbone and at least one side group, wherein the side group comprises a benzene ring-based chromophore comprising a ketone at the 1-position, a substituted or unsubstituted amino group at the 2-position, and an oxygen atom at the 3-position of the benzene ring, wherein the chromophore does not comprise an amino acid group.
A composition comprising:
- a polymer consisting essentially of a polymer backbone and at least one side group, wherein the side group comprises a benzene ring comprising a chromophore comprising a ketone at the 1-position, a substituted or unsubstituted amino group at the 2-position, and an oxygen atom at the 3-position of the benzene ring, wherein the chromophore does not comprise an amino acid group.
Dependencies are inferred from the claim text.