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US 8,026,216 B2Granted
Methods and compositions for contributing to the treatment of cancers
AssigneesSpectrum Pharmaceuticals, Inc., The Board of Trustees of the University of Illinois
InventorsAnil Gulati, Guru Reddy, Luigi Lenaz
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Abstract
Methods and compositions for contributing to the treatment of cancers, especially ovarian tumors, are disclosed. The methods and compositions utilize an endothelin B agonist (ETB) to enhance the delivery and resulting efficacy of chemotherapeutic agent(s) (e.g., cisplatin and/or cyclophosphamide).
Claims11
A method of contributing to the treatment of cancer comprising administering an endothelin B (ETB) receptor agonist and a chemotherapeutic agent;
- wherein said ETB receptor agonist consists of IRL 1620, and wherein said cancer is an ovarian tumor.
A composition comprising at least one chemotherapeutic agent, IRL-1620, and an optional excipient.
Dependencies are inferred from the claim text.