Methods for treating muscle diseases and disorders
AssigneeAcorda Therapeutics, Inc.
InventorsRobert Sklar, Mark Marchionni, David I. Gwynne
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Abstract
The invention relates to methods of treating diseases and disorders of the muscle tissues in a vertebrate by the administration of compounds which bind the p185erbB2 receptor. These compounds are found to cause increased differentiation and survival of cardiac, skeletal and smooth muscle.
Claims1
A method of treating a patient with a skeletal muscle disease comprising administering to the patient a polypeptide comprising an epidermal growth factor-like (EGFL) domain having an amino acid sequence encoded by of SEQ ID NO:154, SEQ ID NO:155, SEQ ID NO:156, SEQ ID NO:157, SEQ ID NO:158, or SEQ ID NO:159 wherein the disease is Duchennes muscular dystrophy.
Dependencies are inferred from the claim text.