Method of preparing a macromolecule deterrent surface on a pharmaceutical package
AssigneeSchott AG
InventorsDaniel Haines, Luis Burzio, Matthias Bicker, Robert Hormes, Horst Koller, Jasmina Buki, Hartmut Bauch, Manfred Lohmeyer
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Abstract
A method of preparing a macromolecule deterrent surface on a pharmaceutical package. In particular, the present invention relates to a method of preparing a protein deterrent surface on a pharmaceutical package by applying a coating or coatings directly to the pharmaceutical package that reduces the adsorption of proteins onto pharmaceutical packaging while not affecting the activity of the protein solution contained.
Claims26
A method of preparing a protein deterrent surface on a pharmaceutical package comprising:
- depositing a polyether coating onto a surface of a pharmaceutical package by plasma chemical vapor deposition wherein said pharmaceutical package acts as a coating chamber,
- wherein the coating is deposited while maintaining a positive temperature difference between the pharmaceutical package and the reaction gas.
A method of preparing a protein deterrent surface on a pharmaceutical package comprising:
- depositing a polyether coating onto a surface of a pharmaceutical package by plasma chemical vapor deposition wherein said pharmaceutical package acts as a coating chamber, wherein the pharmaceutical package is made from a metal or an alloy.
A method of preparing a protein deterrent surface on a pharmaceutical package comprising:
- depositing a polyether coating onto a surface of a pharmaceutical package by plasma chemical vapor deposition wherein said pharmaceutical package acts as a coating chamber and is made of a polymeric material,
- wherein the polymeric material is cyclic olefin polymer, cyclic olefin copolymer, cyclic olefin resin or cyclic olefin-ethylene copolymer.
Dependencies are inferred from the claim text.