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US 8,025,893 B2Granted
Use of a specific inhibitor of hedgehog/smoothened signaling on hyperpigmented skin to obtain decrease of pigmentation
AssigneeSinan Tas
InventorsSinan Tas, Oktay Avci
Life of this patent
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Abstract
Cyclopamine or a similarly specific inhibitor of Hedgehog/Smoothened (Hh/Smo) signaling can be used for obtaining decrease of pigmentation of hyperpigmented skin areas.
Claims4
A method for causing decrease of pigmentation in hyperpigmented skin areas of a human, comprising
- administration of cyclopamine or another compound that selectively inhibits Hedgehog/Smoothened signaling,
- wherein said administration is in a dosage that provides decrease of pigmentation in said skin areas.
A method, for causing decrease of pigmentation in hyperpigmented skin areas of a human, comprising
- administration of cyclopamine or another compound that binds to the same biological target as cyclopamine to inhibit Hedgehog/Smoothened signaling,
- wherein said compound is applied in a cosmetic formulation and in a dosage that provides decrease of pigmentation in said skin areas.
Dependencies are inferred from the claim text.