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US 8,013,169 B2Granted
Naphthylmethylimidizoles as therapeutic agents
AssigneeAllergan, Inc.
InventorsTodd M. Heidelbaugh, Phong X. Nguyen, Ken Chow, Michael E. Garst
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Abstract
Disclosed herein is a compound of the formula (a): Therapeutic methods, compositions and medicaments related thereto are also disclosed.
Claims13
A compound of the formula:
- wherein R1 is H, C1-4 alkyl, or CF3;
- and,
- R2 and R3 are independently H, C1-4 alkyl, C1-5 acyl, cyano, alkylsulfonamide or arylsulfonamide,
- R4 is hydrogen or a stable substituent consisting of from 1 to 8 heavy atoms and any required hydrogen atoms, said heavy atoms being selected from the group consisting of C, N, O, S, F, Cl, Br, I and any combination thereof wherein the stable substituent is selected from the group consisting of alkyl, alkenyl, alkynyl, phenyl, alkoxy, mercaptoalkyl, acyloxy, amino, halo, CH2CN, CN, NO2 and OH;
- and n is 0, 1, 2 or 3.
2 more elements
Dependencies are inferred from the claim text.