Back to results
US 8,013,149 B2Granted
Methods and intermediates for the synthesis of porphyrins
AssigneeNorth Carolina State University
InventorsJonathan S. Lindsey, Masahiko Taniguchi, Arumugham Balakumar, Dazhong Fan
Life of this patent
Estimating the term…
Abstract
A method of making a porphyrin (I) is carried out by condensing (i) a bis(imino)dipyrromethane of Formula II: with (ii) a dipyrromethaneto produce a reaction product; then (b) optionally oxidizing said reaction product with an oxidizing agent; and then (c) optionally demetallating said reaction product to produce the porphyrin. Methods of making compounds of Formula II are also described.
Claims12
A compound of Formula II:
- wherein:
- R is alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, cycloalkylalkenyl, cycloalkylalkynyl, aryl, arylalkyl, arylalkenyl, arylalkynyl, alkoxy, or acyl;
- R1 is H, alkyl or aryl;
- R2, R3, R4, and R5 are each independently selected from the group consisting of H, halo, loweralkoxy, and loweralkylthio;
- and
- A is aryl.
3 more elements
A method of making a compound of Formula II:
- wherein:
- R is alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, cycloalkylalkenyl, cycloalkylalkynyl, aryl, arylalkyl, arylalkenyl, arylalkynyl, alkoxy, or acyl;
- R1 is H, alkyl or aryl;
- R2, R3, R4, and R5 are each independently selected from the group consisting of H, halo, loweralkoxy, and loweralkylthio;
- and
- A is aryl;
- said method comprising:
- reacting a dipyrromethane of Formula IV:
- wherein A, R1, R2, 4 and R5 are as given above, with a compound of Formula V:
- wherein R is as given above in an organic solvent to produce said compound of Formula II.
7 more elements
Dependencies are inferred from the claim text.