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US 8,012,947 B2Granted
Methods and compositions for promoting wound healing
AssigneeHospital for Special Surgery
InventorsMarjana Tomic, Carl Peter Blobel, Asheesh Harsha
Life of this patent
Estimating the term…
Abstract
Provided herein are compositions and methods that inhibit expression of Adam12 gene products, such as ADAM12 mRNA and/or ADAM12 polypeptides, as a therapeutic approach for the treatment of, or promotion of healing of, wounds.
Claims13
A method of promoting healing of a chronic wound, comprising:
- administering to the wound an amount of a selective ADAM12 inhibitory compound effective to promote healing of the wound,
- in which the ADAM12 inhibitory compound inhibits expression of mRNA encoding ADAM12.
A method of promoting healing of a chronic wound, comprising:
- administering to the wound an amount of a selective ADAM12 inhibitory compound effective to promote healing of the wound,
- in which the ADAM12 inhibitor compound is an antibody.
Dependencies are inferred from the claim text.