Contraceptives based on SP22 and SP22 antibodies

A contraceptive vaccine comprising the SP22 polypeptide of SEQ ID NO:

• 2 or a fragment thereof, wherein the fragment comprises a sequence selected from the group consisting of amino acids 34-48 of SEQ ID NO:
• 2, amino acids 43-57 of SEQ ID NO:
• 2, amino acids 47-102 of SEQ ID NO:
• 2, amino acids 88-102 of SEQ ID NO:
• 2, amino acids 118-132 of SEQ ID NO:
• 2, amino acids 136-150 of SEQ ID NO:
• 2, and amino acids 160-174 of SEQ ID NO:
• 2, and a pharmaceutically acceptable carrier.