Peripheral nervous system specific sodium channel nucleic acids
AssigneeThe Research Foundation of State University of New York
InventorsGail Mandel, Simon Halegoua
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Abstract
Cloning, expression, viral and delivery vectors and hosts which contain nucleic acid coding for at least one peripheral nervous system specific (PNS) sodium channel peptide (SCP), isolated PNS SCP, and compounds and compositions and methods, are provided, for isolating, crystallizing, x-ray analyzing molecular modeling, rational drug designing, selecting, making and using therapeutic or diagnostic agents or ligands having at least one peripheral nervous system specific (PNS) sodium channel (SC) modulating activity.
Claims8
An isolated polynucleotide of 10 to 100 nucleotides in length, wherein the polynucleotide is complementary over its length to a corresponding segment having at least 90% sequence identity to SEQ ID NO:9.
Dependencies are inferred from the claim text.