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US 8,012,743 B2Granted
Detection of target analytes using particles and electrodes
AssigneeOsmetech Technology Inc.
InventorsCynthia C. Bamdad, Robert C. Mucic
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Abstract
The invention relates to the use of particles comprising binding ligands and electron transfer moieties (ETMs). Upon binding of a target analyte, a particle and a reporter composition are associated and transported to an electrode surface. The ETMs are then detected, allowing the presence or absence of the target analyte to be determined.
Claims8
A composition comprising:
- a) a substrate comprising an array of working electrodes, wherein each electrode comprises a first binding ligand;
- b) a plurality of colloids, each comprising:
- i) a second binding ligand;
- and
- ii) an electron transfer moiety;
- and
- c) a detector capable of detecting a voltage associated with electron transfer from said electron transfer moiety.
4 more elements
Dependencies are inferred from the claim text.