Method for determining if a subject having type II diabetes has a kidney disorder
AssigneesNederlandse Organisatie voor Toegepast-Natuurwetenschappelijk Onderzoek, Leids Universitair Medisch Centrum
InventorsJohan Hendrikus Verheijen, Jan Roeland Occo Hanemaaijer, Michaela Diamant
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Abstract
The present invention relates to a method for determining if a subject having Type II diabetes has a kidney disorder by measuring the level of matrix metalloproteinase 8 (MMP-8) in the urine of a subject having Type II diabetes and comparing this level to a reference sample or a sample from a healthy subject and determining if the subject has a kidney disorder base on the presence of increased levels of MMP-8 in the urine compared to the reference values or reference sample.
Claims2
A method for determining whether subject having Type II diabetes has a kidney disorder, the method comprising the steps of:
- a) providing a urine sample from the subject having Type II diabetes;
- b) determining in the urine sample the level of matrix metalloproteinase-8 (MMP-8);
- and
- c) comparing one or more of the values determined in step b) with a reference value or reference sample from a healthy individual;
- and
- d) determining whether the subject has a kidney disorder based on the presence of increased levels of MMP-8 in the urine compared to the reference values or reference sample.
Dependencies are inferred from the claim text.