Flexible bone composite
AssigneeSynthes USA, LLC
InventorsSean Kerr, James W. Dwyer
Life of this patent
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Abstract
The present invention relates in general to implantable flexible bone composites, and method for preparing the same. The flexible bone composite includes at least one polymeric layer and at least one calcium-containing layer. The polymeric layer can be a polymeric layer including a synthetic polymer. The calcium-containing layer can include a calcium compound such as β-Ca3(PO4)2. The flexible bone composites of the invention are useful as bone void fillers and have improved handling characteristics.
Claims23
A flexible bone composite comprising:
- (a) a first polymeric layer comprising a synthetic resorbable polymer and having a first side and a second side;
- and
- (b) a first calcium-containing layer comprising granules of β-Ca3(PO4)2 attached chemically, physically, or both to the first side of the polymeric layer, wherein the first polymeric layer has perforations therein, wherein the first calcium-containing layer is substantially free of polymer, and wherein a majority of the external surface of the granules is not covered with polymer.
A flexible bone composite comprising:
- (a) a first polymeric layer comprising a synthetic resorbable polymer and having a first side and a second side;
- and
- (b) a first calcium-containing layer comprising granules of a calcium compound attached physically, chemically, or both to the first side of the polymeric layer, wherein the first polymeric layer has perforations therein, and wherein a majority of the external surface of the calcium compound is not covered with polymer.
A multi-layer flexible bone composite having an exterior and an interior and comprising:
- (a) a first composite comprising:
- a first polymeric layer comprising a synthetic polymer and having a first side and a second side;
- and
- a first calcium-containing layer attached physically, chemically, or both to the first side of the first polymeric layer;
- and
- (b) a second composite comprising:
- a second polymeric layer comprising a synthetic resorbable polymer and having a first side and a second side;
- and
- a second calcium-containing layer attached physically, chemically, or both to the first side of the second polymeric layer,
- wherein the first composite is attached physically, chemically, or both to the second composite to form a multi-layer flexible bone composite having alternating polymeric layers and calcium-containing layers, wherein at least one of the first polymeric layer and second polymeric layer has perforations therein, wherein at least one of the first calcium-containing layer and second calcium-containing layer is substantially free of polymer, wherein at least one of the first calcium-containing layer and second calcium-containing layer includes granules of a calcium compound, and wherein a majority of the external surface of the calcium compound is not covered with polymer.
Dependencies are inferred from the claim text.