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AssigneeChung Ang University Industry Academic Cooperation Foundation
InventorsMin Won Lee, Young Wook Choi, Seong Jun Seo, Do Ik Lee, Hyoweon Bang, Chung Soo Lee, Jong Chan Lee, Soon-Chul Myung, Mi-Kyung Lee, Seong Soo Joo, Sun Eun Choi
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The present invention relates to a composition for treating atopic dermatitis comprising hirsutenone as an active ingredient. Hirsutenone as the active ingredient of the present composition decreases the number of eosinophil and the level of IgE increased in atopic dermatitis and remarkably reduces expression amounts of immune regulatory cytokine (e.g., IL-4, IL-5 and IL-13) associated with atopic dermatitis. In addition, hirsutenone decreases COX-2 and iNOS expression. Hirsutenone as the active ingredient of the present composition could be effectively used in drugs, cosmetics and foods for treating atopic dermatitis or relieving a symptom of atopic dermatitis.
A method for treating atopic dermatitis in a subject suffering from atopic dermatitis, which comprises contacting said subject with a composition comprising a therapeutically effective amount of an isolated compound represented by the following formula 1 or administering said composition to said subject;
A method for relieving a symptom of atopic dermatitis in a subject suffering from atopic dermatitis, which comprises contacting said subject with a composition comprising an isolated compound represented by the following formula 1 or administering said composition to said subject;
Dependencies are inferred from the claim text.