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US 8,012,484 B2Granted
Method of treating ischemia reperfusion injury by inhibiting NKT cell activity
AssigneeUniversity of Virginia Patent Foundation
InventorsJoel M. Linden, Courtney M. Lappas, Victor H. Engelhard
Life of this patent
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Abstract
The present invention relates to a method for treating recurrent tumor metastases following liver resection that includes administration of an effective amount of an agonist of A2A adenosine receptors (ARs).
Claims10
A method for treating ischemia reperfusion injury (IRI), comprising:
- administering to a patient in need thereof a therapeutically effective amount of an agent that inhibits Natural Killer T (NKT) cells, wherein the agent is an anti-CD1 antibody or an anti-NK1.1 antibody.
Dependencies are inferred from the claim text.