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US 8,012,481 B2Granted
Composition and method for inducing or restoring locomotor functions in an animal
AssigneeUniversite Laval
InventorPierre Guertin
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Abstract
The present invention relates to the field of neuropathological disorders involving impaired locomotor functions. More specifically, the present invention relates to a composition and method for inducing and restoring locomotor functions, such as basic walking movements in the lower extremities of chronic spinal cord injured animals, such as paraplegic or tetraplegic individuals.
Claims11
A composition for inducing or restoring locomotor functions in an animal, said composition comprising:
- a) at least one dopamine receptor agonist, L-DOPA, and at least one 5-HT1A serotonin receptor agonist;
- or
- b) L-DOPA and at least one 5-HT1A serotonin receptor agonist,
- wherein said locomotor functions being defined as rather well-coordinated and self-sustained weight bearing walking movements.
1 more element
Dependencies are inferred from the claim text.