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US 8,012,473 B2Granted
C3b antibodies and methods for the prevention and treatment of complement-associated disorders
AssigneeGenentech, Inc.
InventorMenno Van Lookeren Campagne
Life of this patent
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Abstract
The present invention concerns antibodies to C3b and the prevention and treatment of complement-associated disorder using such antibodies.
Claims7
An isolated anti-C3b antibody or antigen binding-fragment thereof selectively binding to C3b and not to C3 and inhibiting the binding of C5 to C3b, wherein said antibody comprises the heavy chain CDRH1, CDRH2 and CDRH3 sequences of SEQ ID NOS 2, 3, and 4, respectively and the light chain CDRL1, CDRL2 and CDRL3 sequences of SEQ ID NOS 6, 7, and 8, respectively.
Dependencies are inferred from the claim text.