Apparatus and method for detecting an analyte

An apparatus for processing a sample of biological material, wherein the apparatus comprises:

• A frame comprising the following integrated components:
• a central housing segment comprising a capture medium adapted to isolate an analyte from the sample of biological material;
• wherein the central housing segment comprises a deformable blister,
• a first housing segment configured to receive a sample collection assembly having a first fluid reservoir and the apparatus including a first flow path from the first housing segment to the central housing segment;
• a second housing segment comprising a testing device and the apparatus including a second flow path between the central housing segment and the second housing segment;
• a third housing segment configured to retain at least a portion of the first fluid after it is released from the first fluid reservoir and the apparatus including a third flow path between the central housing segment and third housing segment;
• a fourth housing segment comprising a second fluid reservoir and the apparatus including a fourth flow path between the fourth housing segment and the central housing segment;
• and
• a rotatable valve comprising a seal selector that is configured to seal off the blister in various configurations, thereby adjusting a flow path of fluid through the central housing segment and to selectively close off a plurality of specific pathways between the central housing segment and each of the first, second, third, and fourth housing segments.