Method for preparing biomedical surfaces
AssigneeSyracuse University
InventorsJeremy Gilbert, Zhijun Bai, Nithya Chandrasekaran
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Abstract
A method for selectively dissolving the beta (β) phase of a titanium alloy out of the surface of the alloy, thereby leaving behind a nano-scale porous surface having enhanced bonding properties with either a biological tissue, such as bone, or an adhesive material, such as a polymer or ceramic by immersing the alloy in an ionic aqueous solution containing high levels of hydrogen peroxide and then exposing the alloy to an electrochemical voltage process resulting in the selective dissolution of the beta phase to form a nano-topographic metallic surface.
Claims13
A method of preparing a metallic biomedical surface, comprising the steps of:
- positioning a three-dimensional, non planar surface comprising a titanium alloy having an alpha and a beta phase in an electrochemical cell;
- immersing said alloy in a non-acidic, ionic aqueous electrolyte solution containing hydrogen peroxide;
- cathodically biasing said alloy to a negative voltage state for a first predetermined time period;
- and
- raising the anodic potential of the alloy for a second predetermined period of time to selectively dissolve the beta phase of the alloy.
A method of preparing a metallic biomedical surface, comprising the steps of:
- positioning a titanium alloy in an electrochemical cell;
- immersing said alloy in an ionic aqueous electrolyte solution containing hydrogen peroxide;
- cathodically biasing said alloy to a negative voltage state for a first predetermined time period by electrochemically holding said alloy at a voltage of −1 V;
- and
- raising the anodic potential of the alloy for a second predetermined period of time by anodically scanning said alloy at 1 mV per second to a voltage of 1 V.
A method of preparing a metallic biomedical surface, comprising the steps of:
- positioning a three-dimensional, non planar surface comprising a titanium alloy having an alpha and a beta phase in an electrochemical cell;
- immersing said alloy in a non-acidic, phosphate buffered solution of saline and hydrogen peroxide;
- cathodically biasing said alloy to voltage state of about −1V for a predetermined time period;
- and
- raising the anodic potential of the alloy to a voltage of about to selectively dissolve the beta phase of the alloy.
Dependencies are inferred from the claim text.