Endovascular magnetic method for targeted drug delivery

A kit for endovascular magnetic targeting drug delivery in a vascular wall and adjoining tissues, comprising:

• an endovascular mesh stent with paramagnetic properties implantable in an area of interest by using a first catheter;
• a polymeric magneto-responsive carrying agent in a form of particles, containing a drug injectable into an area of interest;
• at least one temporary catheter for introduction into a right atrium, and/or in ventricles of heart, and/or in a coronary sinus, and/or in a coronary vein, such that a distal end of the temporary catheter is positionable in proximity to the implanted endovascular mesh stent;
• wherein the temporary catheter is adapted to generate a magnetic field at the area of interest;
• and
• wherein the magnetic field is adjustable by means of a permanent magnet and/or a solenoid with the core, connected to an electric power source, wherein the permanent magnet and/or the solenoid is at the distal end of the at least one temporary catheter, and wherein a maximum magnetic field is at the implanted endovascular mesh stent;
• wherein the implanted endovascular mesh stent, upon withdrawal of the temporary catheter, returns to a non-magnetized state,
• wherein a size of the particles is between 0.01-1.0 microns, and
• wherein the magnetic field has a strength of no more than 1 Tesla.