Organocatalyst
AssigneeNational Taiwan Normal University
InventorsKwunmin Chen, Ying-Fang Ting, Hsuan-Hao Kuan, Pang-Min Liu, Chihliang Chang
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Abstract
The present invention provides an organocatalyst of formula (I), wherein R1 is —H, —OH, —O—Si(R4)(R5)(R6) or C1-6alkoxy, in which R4, R5 and R6 are identical or different and independently selected from the group consisting of C1-6alkyl, phenyl and phenyl substituted with C1-6alkyl; R2 is —OH or ═O; X1 is one selected from the group consisting of —NH—, —S— and X2 is one selected from the group consisting of —C(═O)—, —CH2— and and X1 is different from X2. The high yield and enantioselectivity of an addition reaction are obtained by using the organocatalyst of the present invention.
Claims5
An organocatalyst of formula (I),
- wherein R1 is —H, —OH, —O—Si(R4)(R5)(R6) or C1-6alkoxy, in which R4, R5 and R6 are identical or different and independently selected from the group consisting of C1-6alkyl;
- phenyl and phenyl substituted with C1-6alkyl;
- and
- X1 is different from X2, wherein:
- X1 is —S—;
- X2 is —CH2—;
- and R2 is —OH or ═O, or
- X1 is
- X2 is —CH2—;
- and R2 is —OH or ═O.
Dependencies are inferred from the claim text.