Organic compounds

A process for preparing compounds of formula I

• or a solvate or hydrate thereof, where
• R is phenyl that is unsubstituted or is substituted by 1, 2 or 3 substituents selected from the group consisting of halogen, C1-C7-alkyl, trifluoromethyl, hydroxy and C1-C7-alkoxy;
• R1 is hydrogen or C1-C7-alkyl;
• R2 is hydrogen, C1-C7-alkyl or phenyl that is unsubstituted or is substituted by 1, 2 or 3 substituents selected from the group consisting of halogen, C1-C7-alkyl, trifluoromethyl, hydroxy and C1-C7-alkoxy;
• R3 is phenyl that is unsubstituted or is substituted by 1, 2 or 3 substituents selected from the group consisting of halogen, C1-C7-alkyl, trifluoromethyl, hydroxy and C1-C7-alkoxy, or R3 is naphthyl, 1H-indol-3-yl or 1-C1-C7-alkyl-indol-3-yl;
• and
• R5 is C3-C8-cycloalkyl, D-azacycloheptan-2-on-3-yl or L-azacycloheptan-2-on-3-yl,
• the process comprising the steps of:
• (a) reacting a compound of formula II
• where R1, R2, R3 and R5 are as defined in this claim above and T is a BOC protecting group, with a base to form a compound of formula III
• where R1, R2, R3 and R5 are defined in this claim above;
• and
• (b) reacting a compound of formula III where R1, R2, R3 and R5 are as defined in this claim above with a compound of formula IV
• where R is phenyl that is unsubstituted or is substituted by 1, 2 or 3 substituents selected from the group consisting of halogen, C1-C7-alkyl, trifluoromethyl, hydroxy and C1-C7-alkoxy, and X is halo, in the presence of a base to form a compound of formula I, and
• (c) optionally, forming a desired solvate or hydrate thereof.