Nucleic acids for inhibiting hairless protein expression and methods of use thereof
AssigneeThe Trustees of Columbia University in the City of New York
InventorAngela M. Christiano
Life of this patent
Estimating the term…
Abstract
The present invention provides DNAzymes and ribozymes that specifically cleave Hairless protein mRNA. The present invention also provides antisense oligonucleotides that specifically inhibit translation of Hairless Protein mRNA. The present invention also provides various methods of inhibiting the expression of Hairless Protein. Finally the invention provides pharmaceutical compositions containing the instant DNAzymes, ribozymes and antisense oligonucleotides as active ingredients.
Claims6
An oligonucleotide that specifically hybridizes to Hairless Protein mRNA so as to inhibit the translation thereof in a cell, wherein the oligonucleotide comprises consecutive nucleotides having the sequence of SEQ ID NO:27.
Dependencies are inferred from the claim text.