Polynucleotide fragments of an infectious human endogenous retrovirus
AssigneeAvir Green Hills Biotechnology Research Development Trade AG
InventorsKlaus Wolff, Hubert Pehamberger, Andreas Grassauer, Thomas Muster
Life of this patent
Estimating the term…
Abstract
Nucleotide sequences and fragments which code for a human endogenous retrovirus which is infectious. “Fragments” according to the present invention relate also to specific fragments of the sequences inserted into the vector pCR4-Topo and deposited as MERV-env, MERV-gag, MERV-prt and MERV-pol as mentioned above. Additionally, methods of using such sequences, polypeptides encoded by such sequences, antibodies directs against such sequences, and methods and compositions relating to the same are all contemplated.
Claims13
An isolated polynucleotide molecule comprising a nucleotide sequence of an infectious human endogenous retrovirus, which sequence is or is complementary to a sequence which:
- (a) has at least 99% identity to the full length of SEQ ID NO:1;
- (b) has 100% identity to a fragment of SEQ ID NO:1, the fragment comprising at least 15 contiguous nucleotides of SEQ ID NO:1 and including at least one of nucleotides 416, 602, 630, 639, 654, 738, 799, 802, 866, 945, 953, 972, 1149, 1348, 1413, 1642, 1653, 1668, 1701, 1989, 2068, 2087, 2090, 2097, 2100, 2124, 2163, 2198, 2238, 2253, 2273, 2305, 2313, 2330, 2461, 2808, 2815, 2816, 2878, 2938, 2974, 3052, 3091, 3105, 3124, 3178, 3363, 5402, 5719, 6456, 6458, 6464, 6802, 7146, 7262, 7340, 7347, 7388, or 7436 of SEQ ID NO:1;
- and/or
- (c) comprises the sequence inserted into a vector pCR4-Topo and deposited as any of “MERV-env”, “MERV-gag”, “MERV-prt” and “MERV-pol” at the DSMZ on 26 Sep. 2001.
Dependencies are inferred from the claim text.