Fusion protein having the enhanced in vivo activity of erythropoietin
AssigneeCj Cheiljedang Corporation
InventorsDong-Eok Lee, Myung-Suk Oh, Ki-Wan Kim, Bo-Sup Chung, Byung-Jhip Ha, Ji-Sook Park
Life of this patent
Estimating the term…
Abstract
The present invention relates to a fusion protein in which a carboxy terminal of human erythropoietin (EPO) is fused with a carboxy terminal peptide fragment of β subunit of human chorionic gonadotropin (HCG), to DNA encoding the fusion protein, and to a method for preparation of the fusion protein. The fusion protein has the enhanced in vivo activity of erythropoietin.
Claims4
A fusion protein of human erythropoietin (EPO) with a carboxy terminal peptide (CTP) of human chorionic gonadotropin (HCG) β subunit, consistinq of the amino acid sequence of SEQ ID NO:
- 13.
A fusion protein of human erythropoietin (EPO) with a carboxy terminal peptide (CTP) of human chorionic gonadotropin (HCG) β subunit, consisting of the amino acid sequence of SEQ ID NO:
- 2.
Dependencies are inferred from the claim text.