Pentafluorosulfanylbenzoylguanidines, processes for their preparation, their use as medicaments or diagnostic aids, and medicaments comprising them

A method for the treatment of arrhythmias, life-threatening cardiac ventricular fibrillation, myocardial infarction, angina pectoris, ischemic states of the heart, heart failure or congestive heart failure in a subject in need thereof, said method comprising the administration to said subject a therapeutically effective amount of a pentafluorosulfanylbenzoylguanidine compound of the formula I or II

• in which
• R1 is hydrogen, alkyl having 1, 2, 3 or 4 carbon atoms, alkoxy having 1, 2, 3 or 4 carbon atoms, F, Cl, Br, I, CN, NR10R11, —Op—(CH2)n—(CF2)o—CF3 or —(SOm)q—(CH2)r—(CF2)s—CF3;
• R10 and R11
• are, independently of one another, hydrogen, alkyl having 1, 2, 3 or 4 carbon atoms or —CH2—CF3;
• m is zero, 1 or 2
• n, o, p, q, r and s
• are, independently of one another, zero or 1;
• R2 is hydrogen, F, Cl, Br, I, —CN, —SO2CH3, —(SOh)z—(CH2)k —(CF2)l—CF3, alkyl having 1, 2, 3, 4, 5 or 6 carbon atoms, cycloalkyl having 3, 4, 5, 6, 7 or 8 carbon atoms, or —O-phenyl, wherein the phenyl is unsubstituted or substituted by 1, 2 or 3 radicals selected from the group consisting of F, CI, Br, and I;
• h is zero, 1 or 2;
• z is zero or 1;
• k is zero, 1, 2, 3 or 4;
• 1 is zero or 1;
• R3 and R4
• are, independently of one another, hydrogen or F;
• or a pharmaceutically acceptable salt thereof.