Ion channel modulating compounds and uses thereof
AssigneeCardiome Pharma Corp.
InventorsGregory N. Beatch, Bertrand M. C. Plouvier, Tao Sheng, Michael J. A. Walker, Richard A. Wall, Sandro L. Yong, Jeff Jiqun Zhu, Alexander R. Zolotoy
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Abstract
Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.
Claims19
A method of reducing recurrence of postoperative arrhythmia following cardiac surgery, comprising administering to a patient having undergone cardiac surgery a therapeutically effective amount of a composition comprising a compound having the following structure:
- as an isolated enantiomeric or diastereomeric isomer or as a mixture thereof, or as a pharmaceutically acceptable salt thereof, in combination with a pharmaceutically acceptable carrier, excipient or diluent.
Dependencies are inferred from the claim text.