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US 8,008,337 B2Granted
Azabicyclo[3.2.0] hept-3-yl compounds, a process for their preparation and pharmaceutical compositions containing them
AssigneeLes Laboratoires Servier
InventorsPatrick Casara, Anne-Marie Chollet, Alain Dhainaut, Pierre Lestage, Fany Panayi
Life of this patent
Estimating the term…
Abstract
Compounds of formula (I): wherein: ALK represents an alkylene chain, W represents a group wherein R and R′ are as defined in the description. Medicinal products containing the same which are useful in the treatment of conditions associated with central histaminergic systems.
Claims24
A compound selected from those of formula (I):
- wherein:
- ALK represents an alkylene chain,
- W represents
- in which R and R′, each independently of the other, represent a hydrogen atom or a linear or branched (C1-C6)alkyl group optionally substituted by one or more groups selected from halogen, hydroxy and alkoxy,
- it being understood that:
- the term “alkylene” means a linear or branched divalent radical having from 2 to 6 carbon atoms,
- the term “alkoxy” means an alkyl-oxy group in which the alkyl chain, which is linear or branched, has from 1 to 6 carbon atoms,
- its enantiomers, diastereoisomers, and addition salts thereof with a pharmaceutically acceptable acid or base.
5 more elements
A compound selected from those of formula (VI):
- wherein ALK represents an alkylene chain.
A compound selected from those of formula (VII):
- wherein ALK represents an alkylene chain.
A compound selected from those of formula (VIII):
- wherein ALK represents an alkylene chain and R″ represents a linear or branched (C1-C6)alkyl group or a benzyl group.
A compound selected from those of formula (IX):
- wherein ALK represents an alkylene chain.
Dependencies are inferred from the claim text.