Substituted pyrazolopyridines, compositions containing them, method for the production thereof, and their use

A compound of formula (I):

• in which:
• 1) A is selected from the group consisting of:
• aryl, heteroaryl, substituted aryl, substituted heteroaryl, cycloalkyl, substituted cycloalkyl, heterocyclyl, and substituted heterocyclyl;
• 2) L is selected from the group consisting of:
• bond, CO, NH, CO—NH, NH—CO, NH—SO, NH—SO2, SO2NH, NH—CH2, CH2—NH, CH2—CO—NH, NH—CO—CH2, NH—CH2—CO, CO—CH2—NH, NH—CO—NH, NH—CS—NH, NH—CO—O, and O—CO—NH;
• 3) Ar-L-A is
• in which X2 is N, which may be substituted or unsubstituted;
• 4) one from among X, Y and Z is chosen from N and NO, and two others from among Z, Y and X are C(R5) and C(R6);
• 5) R5 and R6 are independently selected from the group consisting of:
• H, halogen, R2, CN, O(R2), OC(O)(R2), OC(O)N(R2)(R3), OS(O2)(R2), N(R2)(R3), N═C(R2)(R3), N(R2)C(O)(R3), N(R2)C(O)O(R3), N(R4)C(O)N(R2)(R3), N(R4)C(S)N(R2)(R3), N(R2)S(O2)(R3), C(O)(R2), C(O)O(R2), C(O)N(R2)(R3), C(═N(R3))(R2), C(═N(OR3))(R2), S(R2), S(O)(R2), S(O2)(R2), S(O2)O(R2), and S(O2)N(R2)(R3);
• in which each R2, R3 and R4 is independently selected from the group consisting of H, alkyl, alkylene, alkynyl, aryl, heteroaryl, cycloalkyl, heterocyclyl, substituted alkyl, substituted alkylene, substituted alkynyl, substituted aryl, substituted heteroaryl, substituted cycloalkyl, substituted heterocyclyl, alkylene, substituted alkylene, and substituted alkynyl;
• in which R2 and R3 may be linked together to form a 4- to 8-membered ring containing from 1 to 3 hetero atoms chosen from O, N and S;
• or a pharmaceutically acceptable salt thereof.