Bicyclic oxomorpholine derivative

A compound represented by formula (I):

• wherein (1) R1 represents a C1-3 alkyl group, R2 represents a hydrogen atom or a C1-3 alkyl group, or (2) R1 and R2, together with the carbon atom to which they are attached, form a C3-6 cycloalkyl group,
• Ar represents a phenyl group which may be substituted with 1 to 3 substituents that are the same or different and selected from substituent group A1 or a pyridinyl group which may be substituted with 1 to 3 substituents that are the same or different and selected from substituent group A1,
• X represents a methylene group which may be substituted with 1 or 2 substituents selected from substituent group A1 or a vinylene group which may be substituted with 1 or 2 substituents selected from substituent group A1, an oxygen atom, or an imino group which may be substituted with a C1-6 alkyl group or a C1-6 acyl group, and n and m are the same or different and integers of 0 to 2, or a pharmacologically acceptable salt thereof;
• Substituent group A1:
• (1) a halogen atom, (2) a hydroxyl group, (3) a cyano group, (4) a C3-8 cycloalkyl group, (5) a C3-8 cycloalkoxy group, (6) a C1-6 alkyl group (the C1-6 alkyl group may be substituted with 1 to 5 halogen atoms or 1 to 3 C1-6 alkoxy groups), (7) an amino group which may be substituted with 1 or 2 C1-6 alkyl groups (the C1-6 alkyl group may be substituted with 1 to 5 halogen atoms), (8) a C1-6 alkoxy group (the C1-6 alkoxy group may be substituted with 1 to 5 halogen atoms), and (9) a carbamoyl group which may be substituted with 1 or 2 C1-6 alkyl groups (the C1-6 alkyl group may be substituted with 1 to 3 halogen atoms).