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US 8,008,249 B2Granted
Neuregulins for prevention and treatment of damage from acute assault on vascular and neuronal tissue and as regulators of neuronal stem cell migration
AssigneeMorehouse School of Medicine
InventorByron D. Ford
Life of this patent
Estimating the term…
Abstract
Neuregulin, a known neuroprotein, has been found to ameliorate or prevent damage caused by mechanical or chemical assault to blood vessels and, when administered into the cerebral spinal fluid, can ameliorate damage to neuronal tissue caused by stroke or inflammation. Additionally, neuregulin has been found to be useful for enhancement of stem cell migration from the ventricle to the site of injury to the brain.
Claims4
A method for enhancing migration of stem cells from a ventricle into an area of the brain damaged by an assault, comprising:
- administering to a subject in need of such treatment an effective amount of neuregulin-1 after the initial inflammation due to the assault has subsided, wherein said neuregulin-1 is administered via intrathecal route and at intervals of one week or longer.
Dependencies are inferred from the claim text.