Natriuretic peptides for diagnosing cardiac complications due to coronary catheterization
AssigneeRoche Diagnostics Operations, Inc.
InventorsGeorg Hess, Andrea Horsch, Dietmar Zdunek
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Abstract
The present invention discloses a method for diagnosing a cardiac complication in a patient due to coronary catheterization, comprising the steps of (a) obtaining at least one baseline sample from the patient during or after coronary catheterization, and then (b) obtaining at least one test sample from the patient after coronary catheterization, (c) determining a change of the level of an ANP-type peptide between the baseline sample and the test sample, wherein a significant decrease in the level of the ANP-type peptide according to step c) indicates a cardiac complication.
Claims15
A method for diagnosing in a patient a cardiac complication caused by coronary catheterization, the method comprising the steps of
- measuring a level of NT-proANP in at least one baseline sample which has been obtained from the patient during or after coronary catheterization,
- measuring a level of NT-proANP in at least one test sample which has been obtained from the patient after coronary catheterization, and
- determining an amount of change of the level of NT-proANP between the baseline sample and the test sample, wherein a decrease in the level of NT-proANP indicates a cardiac complication.
A method for diagnosing a cardiac complication in a patient due to coronary catheterization, comprising the steps of
- measuring a level of NT-proANP in at least one baseline sample obtained from the patient during or after coronary catheterization,
- measuring a level of NT-proANP in at least one test sample obtained from the patient after coronary catheterization,
- determining a change of the level of NT-proANP between the baseline sample and the test sample, and
- determining a change of a level of NT-proBNP between the baseline sample and the test sample, wherein a decrease in the level of NT-proANP according to the determination step concomitant with an increase of level of NT-proBNP indicates a cardiac complication.
Dependencies are inferred from the claim text.