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US 8,008,013 B2Granted
Predicting and diagnosing patients with autoimmune disease
AssigneeOklahoma Medical Research Foundation
InventorsPatrick M. Gaffney, Kathy L. Moser
Life of this patent
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Abstract
The present invention provides methods for the prediction and diagnosis of autoimmune diseases, including Systemic Lupus Erythematosus, using single nucleotide polymorphism in TNFAIP3 (A20).
Claims13
A method of identifying an increased risk of developing systemic lupus erythematosus (SLE) in a human subject comprising:
- (a) obtaining a nucleic acid-containing sample from said subject;
- (b) determining the presence in the sample of an A allele at rs7749323 in a tumor necrosis factor, alpha-induced protein 3 (TNFAIP3) gene, wherein the presence of the A allele at rs7749323 indicates an increased risk for SLE in the subject.
Dependencies are inferred from the claim text.