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US 8,007,992 B2Granted
Method of treating glutaraldehyde-fixed pericardial tissue with a non-aqueous mixture of glycerol and a C1-C3 alcohol
AssigneeEdwards Lifesciences Corporation
InventorsBin Tian, Jim Davidson
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Abstract
A method of treating a biological tissue that enables dry storage of said tissue is disclosed. In one embodiment, the method comprises contacting the biological tissue with a non-aqueous treatment solution comprising a polyhydric alcohol and a C1-C3 alcohol and removing a portion of the treatment solution from the solution-treated biological tissue. Also disclosed is biological tissue prepared using the above process and prosthetic devices made with such tissue.
Claims11
A method of treating a biological tissue, comprising:
- contacting glutaraldehyde-fixed pericardial tissue with a non-aqueous treatment solution comprising a glycerol and a C1-C3 alcohol selected from the group consisting of methanol, ethanol, n-propanol, 2-propanol and mixtures thereof, wherein the glycerol is 60-95% by volume;
- and
- removing a portion of the treatment solution from the solution-treated biological tissue to provide a biological tissue ready for sterilized containment.
Dependencies are inferred from the claim text.