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US 8,007,905 B2Granted
Flat microfibers as matrices for cell growth
Assignee3M Innovative Properties Company
InventorsMario A. Perez, Terry R. Hobbs, Stephanie J. Moeller
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Abstract
The present invention relates to culturing cells utilizing a matrix of microfibrillated thermoplastic polymeric materials. More specifically, the present invention relates to a method of culturing cells. In addition, the invention relates to a microfibrillated article for culturing cells dispersed in a cell culture medium. The matrix of thermoplastic polymeric materials for culturing cells of this invention finds use in tissue engineering and wound healing applications.
Claims14
A method of culturing cells comprising:
- a) providing an article comprising a matrix of oriented, thermoplastic, substantially rectangular microfibers having a rectangular cross-section and having an average effective diameter of 0.01 to 20 micrometers, the matrix dispersed in a cell culture medium;
- b) inoculating the matrix with cells;
- and
- c) incubating the matrix, thereby culturing the cells.
1 more element
Dependencies are inferred from the claim text.