Microporous articles comprising biodegradable medical polymers, method of preparation thereof and method of use thereof

A microporous polymeric article having a target pore diameter dv, comprising an essentially continuous porosity with a controlled void volume from 10 to 90%, wherein pore diameters show a unimodal distribution set at a predefined unimodal peak location corresponding to said target pore diameter dv, and wherein a majority of pores have a diameter d of at least dv−50% and at most dv+50%, prepared according to a method comprising the steps of:

• a) determining a target pore diameter dv;
• b) selecting at least one polymer A and at least one polymer B at least partially immiscible with A, according to the target pore diameter dv determined in step a);
• c) melt blending the selected polymers from step b), thereby preparing a polymer blend, wherein said polymers A and B have an essentially continuous morphology;
• d) cooling said polymer blend to room temperature, thereby retaining its morphology;
• and
• e) extracting said polymer B, at least partially, from the polymer blend by dissolving said polymer B in a solvent that is a non-solvent of polymer A.