US 8,007,812 B2Granted

Flagellin related polypeptides and uses thereof

AssigneeThe Cleveland Clinic Foundation

InventorsAndrei V. Gudkov, Joseph A. DiDonato, Vadim Krivokrysenko

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Abstract

The use of flagellin and flagellin related polypeptides for the protection of mammals from the effects of apoptosis is described.

Claims3

Dependent claims

A method of protecting a mammal from gastrointestinal and hematopoietic radiation syndromes comprising administering to a mammal in need thereof a composition comprising a flagellin polypeptide, wherein the polypeptide comprises the amino acid sequence of SEQ ID NO:

Dependencies are inferred from the claim text.

Facts

Application: 11/722,682Filed 22 Dec 2005 · us provisional application
Priority: 22 Dec 2004
Published: US 2009/0011982 A18 Jan 2009
Granted: 30 Aug 2011
Term ends: Not estimatedThe source records don’t support an estimate.

Classification18 codes

A61K 38/164
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof: from bacteria
A61K 39/0275
Enterobacteriales, e.g. Enterobacter: salmonella
A61K 45/06
Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00: mixtures of active ingredients without…
A61P 17/02
Drugs for dermatological disorders: for treating wounds, ulcers, burns, scars, keloids, or the like

Family

Application60/639,826Us provisional application · filed 22 Dec 2004
US 2009/0011982 A1Pre-grant publication · published 8 Jan 2009
US 8,007,812 B2This patent

From the US filing history. Foreign family members aren’t listed.

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