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US 8,007,810 B2Granted
HLA-A2 tumor associated antigen peptides and compositions
AssigneeBiotech Synergy, Inc.
InventorsJohn D. Fikes, Glenn Ishioka, Alessandro Sette, Robert W. Chesnut
Life of this patent
Estimating the term…
Abstract
A peptide or composition comprising at least one HLA-A2 epitope or analog from CEA, HER2/neu, MAGE2, MAGE3, or p53.
Claims11
A composition, comprising LLTFWNPPV (SEQ ID NO:4), KVFGSLAFV (SEQ ID NO:7), KLBPVQLWV (SEQ ID NO:6), SMPPPGTRV (SEQ ID NO:5), YLSGADLNL (SEQ ID NO:
- 8), IMIGHLVGV (SEQ ID NO:9), KVAEIVHFL (SEQ ID NO:10), RLLQETELV (SEQ ID NO:2), YLQLVFGIEV (SEQ ID NO:3), and aKXVAAWTLKAAa (SEQ ID NO:1), wherein a in SEQ ID NO:1 is any of D-alanine or L-alanine and wherein X in SEQ ID NO:1 is any of cyclohexylalanine, phenylalanine or tyrosine and wherein B in SEQ ID NO:6 is any of α-amino butyric acid or cysteine.
Dependencies are inferred from the claim text.