Methods for treating bone cancer pain by administering a nerve growth factor antagonist antibody
AssigneePfizer Inc.
InventorsDavid L. Shelton, Patrick William Mantyh
Life of this patent
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Abstract
The invention features methods and compositions for preventing or treating bone cancer pain including cancer pain associated with bone metastasis by administering an antagonist of nerve growth factor (NGF). The NGF antagonist may be an anti-NGF (such as anti-hNGF) antibody that is capable of binding hNGF.
Claims12
A method for treating bone cancer pain in an individual comprising administering to the individual an effective amount of a anti-nerve growth factor (NGF) antagonist antibody, wherein the anti-NGF antagonist antibody comprises the amino acid sequence shown in SEQ ID NO:1.
A method for treating bone cancer pain in an individual comprising administering to the individual an effective amount of a anti-nerve growth factor (NGF) antagonist antibody, wherein the anti-NGF antagonist antibody comprises the amino acid sequence shown in SEQ ID NO:2.
Dependencies are inferred from the claim text.