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US 8,007,777 B2Granted
Delivery system for biological component
AssigneeNutraceutix, Inc.
InventorsTanya Borek, Terri Butler, Catherine Federici, Michael P. Hite, Christopher London, Stephen J. Turner
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Abstract
The invention relates to a controlled release formulation for a probiotic. The formulation contains a hydrophilic agent, an electrolytic agent and a polysaccharide and is in the form of a monolithic tablet for oral delivery to the intestinal system. The probiotic can be lactic acid bacteria.
Claims8
A controlled release formulation for oral delivery to an intestinal system, the formulation comprising:
- about 5% to 40% by total weight of at least one of a hydrophilic agent selected from the group consisting of hydroxypropyl methylcellulose and polyethylene oxide;
- about 5% to 40% by total weight of a release modifying agent comprising pectin;
- about 1% to 40% by total weight of at least one of an electrolytic agent selected from the group consisting of sodium carbonate, sodium bicarbonate, sodium phosphate, and calcium carbonate;
- and
- a probiotic;
- wherein said formulation is a monolithic tablet without an enteric coating.
3 more elements
Dependencies are inferred from the claim text.