Purified linear polypeptide epitopes from walnuts and associated methods
AssigneeThe Florida State University Research Foundation, Inc.
InventorsKenneth H. Roux, Shridhar K. Sathe, Jason M. Robotham, Suzanne S. Teuber
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Abstract
A purified Ig-E binding immunogenic polypeptide the amino acid sequence of which consists of SEQ ID NO:1 is disclosed. The purified amino acid sequence is a major allergen of the walnut Juglans regia. Also described are a diagnostic test kit and use of the purified polypeptide in tests for identifying patients having an allergy to walnuts. Mutations of the disclosed polypeptide, as well as nucleic acid sequences encoding therefor are claimed as part of the invention.
Claims3
A test for detecting a walnut allergy in a patient, the test comprising:
- contacting the patient with an effective amount of a purified polypeptide consisting of SEQ ID NO:
- 1;
- and
- detecting whether said contacting the patient results in an allergic response, wherein an allergic response is indicative of a walnut allergy in the patient.
Dependencies are inferred from the claim text.