Pharmaceutical composition of nanoparticles
AssigneesGP Medical, Inc., National Tsing Hua University
InventorsHsing-Wen Sung, Hosheng Tu
Life of this patent
Estimating the term…
Abstract
The invention discloses a pharmaceutical composition of the nanoparticles composed of chitosan, a negatively charged substrate, a transition metal ion, and at least one bioactive agent for drug delivery. The nanoparticles are characterized with a positive surface charge configured for promoting enhanced permeability for bioactive agent delivery.
Claims19
A pharmaceutical composition of nanoparticles, the nanoparticles consisting of a shell portion that is dominated by positively charged chitosan and a core portion, wherein the core portion consists of the positively charged chitosan, a transition metal ion, one negatively charged substrate, at least one bioactive agent loaded within the nanoparticles, and optionally a zero-charge compound.
Dependencies are inferred from the claim text.