Microarray bioprobe device integrated with an amplifier having bottom-gate thin film transistors

A microarray bioprobe device integrated with an amplifier having bottom-gate thin film transistors comprising:

• a first flexible substrate having a plurality of first conducting wires formed therein, by which electrical transmission is generated between a first and second surfaces of said first flexible substrate;
• a plurality of biological probes formed on said first surface of said first flexible substrate, each of said biological probes electrically connecting with corresponding one of said conducting wires respectively;
• a second flexible substrate having a plurality of second conducting wires formed therein, by which an electrical transmission is generated between an upper and lower surfaces of said second flexible substrate, and said lower surface of said second flexible substrate is electrically jointed to said second surface of said first flexible substrate;
• and
• at least one amplifier having bottom-gate thin film transistors and a plurality of lead wires formed on said upper surface of said second flexible substrate, wherein each of said lead wires is electrically connected with corresponding one of said second conducting wires respectively;
• wherein each said bottom-gate thin film transistor comprises a bottom gate formed on said upper surface of said second flexible substrate, a pair of source/drain and a channel formed above said bottom-gate, electrical signals are transmitted between said biological probes and said amplifier having bottom-gate thin film transistors by said first conducting wires, said second conducting wires and said lead wires.