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US 7,999,071 B2Granted
Human cytotoxic T-lymphoctye epitope and its agonist eptiope from the non-variable number of tandem repeat sequence of MUC-1
AssigneeThe United States of America, as represented by the Secretary, Department of Health and Human Services
InventorsJeffrey Schlom, Kwong-Yok Tsang
Life of this patent
Estimating the term…
Abstract
Novel MUC-1 epitopes outside the VNTR region are identified. In addition, the first agonist epitope of MUC-1 is described. The employment of agonist epitopes in peptide, protein and vector-based vaccine may well aid in the development of effective vaccines for a range of human cancers.
Claims45
An isolated polypeptide up to 12 amino acids in length comprising an amino acid sequence selected from the group consisting of SEQ ID NOs:
- 1 and 14-19.
Dependencies are inferred from the claim text.